In the face of immediate challenges, notably the post-pandemic socio-economic crisis and the war in Ukraine and its repercussions on the energy and food security across the Euro-Mediterranean region, but also the climate emergency threatening the wellbeing of both nature and people, the Union for the Mediterranean (UfM) Secretariat has enhanced in 2022 its action on the 5 priorities retained by the Ministers of Foreign Affairs at the 5th UfM Regional Forum/25th anniversary of the Barcelona Process, in November 2020.