This report aims to provide an overview about the 32 case studies of seven ZeroPollution4Water Cluster projects. These seven projects have received funding under Horizon Europe Research and Innovation programme in 2022 and aim at preventing groundwater pollution and securing drinking water quality. In line with the zero-pollution ambition of the European Green Deal the seven projects will use the case studies to increase the preparedness of the EU water sector for challenges arising from climate change and support EU environmental legislation and policies related to groundwater and drinking water consumer protection. They focus on preventing freshwater pollution, enhancing water quality, and ensuring safe use for both humans and ecosystems, among others. The approach involves the entire drinking water production cycle, with an emphasis on developing innovative and robust monitoring and early-warning systems on drinking water quality, from sources to drinking water supply.