The paper investigates the current state of food security in the Mediterranean. Focusing on Egypt, Lebanon and Tunisia, the paper analyses the main challenges related to food security and relative strategies put in place at the national and regional levels. Moreover, the entrepreneurial perspective on food security-related issues is investigated through a focus group and a survey involving entrepreneurs from INVESTMED project. Finally, the paper provides key policy recommendations adopting an entrepreneurial perspective on food security in the region. Per each food security dimension, the paper highlights the entrepreneurial contribution for its improvement to then formulate the relative policy recommendation.